Selected Publications:
2021 De Lazzari B, Iacovoni A, Mottaghy K, Capoccia M, Badagliacca R, Vizza CD, De Lazzari C. ECMO Assistance during Mechanical Ventilation: Effects Induced on Energetic and Haemodynamic Variables. Comput Methods Programs Biomed. 2021 Feb 14;202:106003. doi: 10.1016/j.cmpb.2021.106003.
2020 Stegmayr B, Willems C, Groth T, Martins A, Neves NM, Mottaghy K, Remuzzi A, Walpoth B. Arteriovenous access in hemodialysis: A multidisciplinary perspective for future solutions. Int J Artif Organs. 2021 Jan;44(1):3-16. doi: 10.1177/0391398820922231.
2019 Poorkhalil A, Mouzakis F, Kashefi A, Mottaghy K. The course of hematocrit value along the length of a dialyzer's fiber: Hemoconcentration modeling and validation methods. Int J Artif Organs. 2019; 42(9): 482‐489. doi:10.1177/0391398819847214
2017 Tran L, Mottaghy K, Arlt-Körfer S, Waluga C, Behbahani M. An experimental study of shear-dependent human platelet adhesion and underlying protein-binding mechanisms in a cylindrical Couette system. Biomed Tech (Berl). 2017 Aug 28;62(4):383-392. doi: 10.1515/bmt-2015-0034.
2016 Poorkhalil A, Amoabediny G, Tabesh H, Behbahani M, Mottaghy K. A new approach for semiempirical modeling of mechanical blood trauma. Int J Artif Organs. 2016; 39(4): 171‐177. doi:10.5301/ijao.5000474
2015 Tabesh H, Elahi Z, Amoabediny G, Kashefi A, Mottaghy K. A Perspective on the Development and Clinical Application of Oxygenators: Past, Present and Future. Journal of Mazandaran University of Medical Sciences (JMUMS).2015; 25(121)
2014 Tabesh H, Amoabediny G, Rasouli A, Ramedani A, Poorkhalil A, Kashefi A, Mottaghy K. Simulation of blood oxygenation in capillary membrane oxygenators using modified sulfite solution. Biophysical chemistry. 2014; 195, 8-15. doi: 10.1016/j.bpc.2014.07.005
2013 Khachab A., Tabesh H., Kashefi A., Mottaghy K.: Novel Concept For Pure Diffusive Capillary Membrane Oxygenators: Silicone Hollow Sphere (SiHSp) Fibers. ASAIO Journal, 59, 162-168.2013
2013 Salehi-Nik N, Amoabediny Gh, Pouran B, Tabesh H, Shokrgozar MA, Haghighipour N, Khatibi N, Anisi F, Mottaghy K, Zandieh-Doulabi B. Engineering Parameters in Bioreactor’s Design: A Critical Aspect in Tissue Engineering. BioMed Research International. 2013. doi: 10.1155/2013/762132
2013 Hermann S., Kashefi A., Mottaghy K., Reilly R.: The Ballistocardiogram as a Contactless Registration Method for Cardiovascular Parameters. Int J Artif Organs, 36(8), 563.
2013 Verkerke GJ, van der Houwen EB, Broekhuis AA, Bursa J, Catapano G, McCullagh P, Mottaghy K, Niederer P, Reilly R, Rogalewicz V, Segers P, Verdonschot N. Science versus design; comparable, contrastive or conducive? Journal of the Mechanical Behavior of Biomedical Materials Volume 21. 2013; 195–201. doi: 10.1016/j.jmbbm.2013.01.009
2012 Tabesh H, Amoabediny Gh, Poorkhalil A, Khachab A, Kashefi A, Mottaghy K. A theoretical model for evaluation of the design of a hollow-fiber membrane oxygenator. Int J Artif Organs. 2012; 15: 347-356. doi: 10.1007/s10047-012-0655-3
2010 Khachab A., Oedekoven B., Hahn A., Mottaghy K.: Effect of pulmonary surfactant on O2 diffusion in a physical Model. Int J Artif Organs, 33(7), 423.
2009 Mottaghy K., Oedekoven B., Hassoun H., Hahn A.: Oxygen Diffusion Through Different Liquid Layers with and Without Surfactant in a Physical Model. Acta Physiologica, 195(669), 5.
2009 Tabesh H, Amoabediny GH, Salehi Nik N, Heydari M, Yousefifard M, Ranaei Siadat SO, Mottaghy K. The role of biodegradable engineered scaffolds seeded with Schwann cells for spinal cord regeneration. Neurochemistry International Journal. 2009; 54:2, 73-83. doi: 10.1016/j.neuint.2008.11.002
2007 Fischer H, Luk M, Oedekoven B, Telle R, Mottaghy K. Hemocompatibility of high strength oxide ceramic materials: An in vitro Study. Journal of Biomed Materials Research Part A. 2007; 982-986. doi: 10.1002/jbm.a.31119
2006 Orfao SMC, Jank G, Mottaghy K. A new mathematical approach to modelling thrombin generation. Int J Artif Organs. 2006 ; 29(7). doi : 10.1177/039139880602900710
2005 Kopp R, Bensberg R, Kashefi A, Mottaghy K, Rossaint R, Kuhlen R. Effect of hirudin versus heparin on hemocompatibility of blood contacting biomaterials: An in vitro study. Int J Artif Organs. 2005; 28(12), 1272-1277. doi: 10.1177/039139880502801211
2005 Salimi S., Henseler A., Motaghy K.: Non Equilibrium O2-Dissociation Curves (ne-ODC): Effect of pO2, Shear Rate and Haematocrit. Int J Artif Organs, 28 (9).
2003 Körfer S, Klaus S, Mottaghy K. Application of Taylor Vortices in Hemocompatibility Investigations. Int J Artif Organs. 2003; 26(4): 331-338. doi : 10.1177/039139880302600408
2002 Kopp R, Mottaghy K, Kirschfink M. Mechanism of Complement Activation during Extracorporeal Blood Biomaterial Interaction: Effects of heparin coated and uncoated surfaces. ASAIO Journal. 2002; 48: 598-605. doi: 10.1097/00002480-200211000-00005
2002 Klaus S, Körfer S, Mottaghy K, Reul H, Glasmacher B. In vitro blood damage by high shear flow: Human versus porcine blood. Int J Artif Organs. 2002 ; 25(4): 306-312. doi : 10.1177/039139880202500409
2001 Eitschberger S, Henseler A, Krasenbrink B, Oedekoven B, Mottaghy K. Investigation on the Ability of an Ultrasound Bubble Detector to Deliver Size Measurements of Gaseous Bubbles in Fluid Lines by Using a Glass Bead Model. ASAIO Journal. 2001; 47: 18-24. doi: 10.1097/00002480-200101000-00006
2000 Radke A, Mottaghy K, Goldmann Ch, Khorram-Sefat R, Kovacs B, Janssen A, Klosterhalfen B, Hafemann B, Pallua N, Kirschfink M.C1 Inhibitor Prevents Capillary Leakage after Thermal Trauma. Critical Care Med. 2000; 28(9): 3224-32. doi: 10.1097/00003246-200009000-00018
2000 Metzler V, Lehmann T, Bienert H, Mottaghy K, Spitzer K. Scale-independent shape analysis for quantitative cytology using mathematical morphology. Computers in Biology and Medicine. 2000; 30: 135-151. doi: 10.1016/S0010-4825(00)00003-2
2000 Graf J, Königs B, Mottaghy K, Janssens U. In vitro validation of gastric air tonometry using perfluorocarbon FC-43 and 0.9% sodium chloride. British Journal of Anaesthesia. 2000; 84(4): 497-9. doi: 10.1093/oxfordjournals.bja.a013477
2000 Keldenich S, Kopp R, Kirschfink M, Klein B, Henseler A, Thelen H, Oedekoven B, Mottaghy K. Application of a New Dynamic Flow Model for Investigating the Biocompatibility of Modified Surfaces. ASAIO Journal. 2000; 46: 134-141. doi: 10.1097/00002480-200001000-00030
1999 Henseler A, Oedekoven B, Andersson C, Mottaghy K. Entwicklung eines modifizierten “Chandler-Loop-Systems” zur Evaluierung der Biokompatibilität von ECC-Schläuchen. Kardiotechnik. 1999; 3: 66-69
1999 Metzler V, Bienert H, Lehmann T, Mottaghy K, Spitzer K. A novel method for quantifying shape deformation applied to biocompatibility testing. ASAIO Journal. 1999; 45: 264-271.doi: 10.1097/00002480-199907000-00004
1998 Khorram-Sefat R, Goldmann CH, Radke A, Lennartz A, Mottaghy K, Afify M, Küpper W, Klosterhalfen B. The Therapeutic Effect of C1-Inhibitor on Gut-Derived Bacterial Translocation After Thermal Injury. Shock. Europe PMC. 1998; 9/2: 101-108. doi: 10.1097/00024382-199802000-00005
1996 Eitschberger S, Krasenbrink B, Henseler A, Oedekoven B, Mottaghy K. Ein optimiertes Verfahren zur Beurteilung des Rückhaltevermögens arterieller Filter für gasförmige Emboli. Kardiotechnik. 1996; 4: 108-112
1996 Neuerburg J, Haupt-Pichler A, Katterbach FJ, Eilers R, Sieß T, Buro K, v. Pichler C, Mottaghy K, Günther RW. Bestimmung der Effektivität perkutaner Kavafilter: Experimentelle Untersuchungen. Fortschr. Röntgenstr. 1996; 164,4: 331-337. Georg Thieme Verlag Stuttgart - New York
1996 Radke A, Kirschfink M, Goldmann Ch, Mottaghy K, Hettich R. The Protective Effect of C1-Inhibitor on Thermal Trauma: First Results from an Animal Study. Biomedical Progress. 1996; 9/1:10.
1995 Mottaghy K. Extracorporeal Lung Support with Heparinized Systems: An Overview on Experimental Investigations. ed: C. Roussos. 8th European Congress of Intensive Care Medicine. 1995 October 18-22. Athens
1994 Beer AM, Dickgreber NJ, Mottaghy K. Untersuchungen zum Gasaustausch unter der Geburt mit besonderer Berücksichtigung der intraerythrozytären Sauerstoff-Sättigung. Hypoxische Gefährdung des Fetus sub partu. 1994. R. Knitza, Steinkopff Verlag. Darmstadt
1993 Kirschfink M, Kovacs B, Mottaghy K. Extracorporeal circulation: In vivo and in vitro analysis of complement activation by heparin-bonded surfaces. Circulatory Shock. Europe PMC. 1993; 40:221-226
1991 Assmann R, Heidelmeyer CF, Trampisch HJ, Mottaghy K, Versprille A, Sandmann W, Falke KJ. Right ventricular function as¬sess¬ed by thermodilution technique during apnea and mechanical ven¬ti¬lation. Critical Care Medicine. Europe PMC. 1991; 19/6: 810-817.doi: 10.1097/00003246-199106000-00014
1991 Mottaghy K, Oedekoven B, Pöppel K, Kovacs B, Kirschfink M, Bruchmüller K, Kashefi A, Geisen C. Heparin-coated versus non-coated surfaces for extra¬cor¬po¬re¬al circulations. Intern. J. Artif. Organs. 1991; 14: 721-728. doi: 10.1177/039139889101401108
1991 Hoffmann BH, Böhm SH, Morris AH, Simon B, Mottaghy K. In vivo demonstration of Haldane Effect during extracorporeal gas exchange. Intern. J. Artif. Organs. 1991; 14/11: 703-706. doi: 10.1177/039139889101401105
1991 Mottaghy K. Measurement of arterial O2-content with galvanic cells. The Oxygen Status of Arterial Human Blood. 1991. eds: R. Zander and F. Mertzlufft. Verlag S. Karger, Basel, München
1990 Jüngling E, Dautzenberg R, Mottaghy K, Kammermaier H. Ein neues Meßgerät zur schnellen Bestimmung des Sauer¬stoff¬gehaltes im Blut und anderen Biofluiden. Biomed. Technik, 35 (Ergänzungsband). 1990; 92-93. doi: 10.1515/bmte.1990.35.s3.92
1990 Geisen C., Mottaghy K., Scheffen I., Kaufmann P.: Effect Of Long-Term Hypoxia On Oxygen Transport Properties of Blood In Pregnant Guinea Pigs. In: Oxygen Transport To Tissue XII. Editors: J.Piiper et al. Plenum Press, New York.
1990 Scheffen I, Kaufmann P, Philippens L, Leiser R, Geisen C, Mottaghy K. Alterations of the fetal capillary bed in the guinea pig placenta following long-term hypoxia. Oxygen Transport to Tissue XII. 1990. eds: J.Piiper, Goldstick T.K., Meyer M. Springer. Boston. doi: 10.1007/978-1-4684-8181-5_89
1990 Kashefi A, Oedekoven B, Mottaghy K. Untersuchungen über die Gasaustauschkapazität von Polypropylenmembran-Oxygenatoren unter standardisierten in vitro Bedingungen. ECC International Band 2. 1990
1989 Mottaghy K, Oedekoven B, Starmans H, Müller B, Kashefi A, Hoffmann B, Böhm S. Technical aspects of plasma leakage prevention in microporous capillary membrane oxygenators. ASAIO Trans. 1989; 35/3: 640-643.doi: 10.1097/00002480-198907000-00154
1989 Mottaghy K, Oedekoven B, Pöppel K, Bruchmüller K, Kovacs B, Spahn A, Geisen C. Heparin free long-term extracorporeal circulation using bioactive surfaces. ASAIO Trans. 1989; 35: 635-637. doi: 10.1097/00002480-198907000-00152
1989 Mottaghy K, Oedekoven B, Schaich-Lester D, Pöppel K. Non heparin and heparin bonded systems for ECCO2-R: An experimental study. Neonatal and Adult Respiratory Failure. Mechanisms and Treatments. 1989; pp.209-220. ed.: J.P. Gille. Edition Scientifiques Elsevier
1989 Mottaghy K, Oedekoven B, Schaich-Lester D, Pöppel K, Küpper W. Application of surfaces with end point attached heparin to ex¬tracorporeal circulations with membrane lungs. ASAIO Trans. 1989;35: 146-152. doi: 10.1097/00002480-198904000-00006
1988 Klein MD, Arensman RM, Weber TR, Mottaghy K, Langer R, Nolte SH. Pediatric ECMO. Directions for new developments. ASAIO Trans. 1988; 34-4: 978-985
1988 Mottaghy K. Messung der arteriellen O2-Konzentration mit galvanischen Zellen. Der Sauerstoff-Status des arteriellen Blutes. 1988; pp.207-215. R. Zander und F. Mertzlufft. Verlag S. Karger Basel
1987 Mottaghy K, Schaich-Lester D, Lester A, Oedekoven B, Assmann R. Long-term extracorporeal CO2-removal in sheep for up to 7 days using capillary fiber membrane oxygenators. ASAIO Trans. 1987;33: 565-569
1986 Mottaghy K, Oedekoven B, Bey R, Schaich-Lester D, Starmans H, Schmid-Schönbein H. Aspects physiologiques de l'elimination extracorporelle du CO2 chez le chien et le mouton en vue d'application cliniques. Innovation et Technologie en Biologie et Medicine 7 numero special. 1986; pp.55-67. eds: A. Lautier and J.P. Gille. Über¬setzung von [30] auf Veranlassung der Herausgeber
1985 Mottaghy K, Oedekoven B, Bey R, Schmid-Schönbein H. Extracorporeal anticoagulation using a serine protease inhibitor in hemodialysis in sheep. Trans. Am. Soc. Artif. Int. Organs 31. 1985; 534-536
1985 Mottaghy K, Bey R, Oedekoven B, Schaich-Lester D, Schmid-Schönbein H. Extracorporeal CO2-removal : Pulmonary and extracorporeal equilibria in dogs and sheep. Europ. Journ. Applied Physiology 54: 1985; 546-553. doi: 10.1007/BF00422967
1984 Mottaghy K, Hanse HJ. Effect of combined shear, secondary flow and axial flow of blood on oxygen uptake. Chem. Eng. Communications. 1984; 36: 269-279. doi: 10.1080/00986448508911259
1984 Oedekoven B, Bey R, Mottaghy K, Schmid-Schönbein H. Gabexate Mesilate (FOY) as an anticoagulant in extracorporeal circulation in dogs and sheep. Thromb. Haemost. 1984; 52-3: 329-332
1984 Mottaghy K, Haest CWM, Cremer J, Derissen W. Oxygen uptake into the sheared flowing blood: Effects of red cell membranes and haematocrit. Oxygen Transport to Tissue-V. 1984; pp.175-185. eds: D.W. Lübbers, H. Acker, E. Leniger-Follert and T.K. Goldstick. Plenum Publishing Corp. New York. doi: 10.1007/978-1-4684-1188-1_11
1983 Bey R, Mottaghy K, Oedekoven B, Schmid-Schönbein H. Prostacyclineinsatz im extrakorporalen Kreislauf an Kaninchen bei gleichzeitiger Reduktion der Heparindosen. Kardiotechnik. 1983; 6-2:67-71
1982 Motthaghy K, Haest CWM, Schleuter HJ. Effect of red cell rigidity on gas transport by sheared flow¬ing blood. Chem. Eng. Communications. 1981; 15: 157-167. doi: 10.1080/00986448208911066
1981 Mottaghy K, Hahn A. Interfacial tension of some biological fluids: A comparative study. Journ. Clinical Chemistry and Laboratory Medicine (CCLM). 1981; 19: 267-271. doi: 10.1515/cclm.1981.19.5.267
1980 Heinsen H, Mottaghy K, Frömel M. Pulmonary and systemic embolism after deliberate intravenous fluorocarbon administration. Virchows Arch A Pathol Anat and Histol. 1980; 386: 331-341. doi: 10.1007/BF00427302
1980 Mottaghy K, Frömel M, Driessen G, Schnittler HJ, Bey R. Intravital microscopical model to study the influence of extracorporeal pumping on the perfusion of microcirculation. Proc. Eur. Soc. Artif. Organs 7. 1980; 274-278
1979 Wurzinger LJ, Baldauf W, Tobias E, Mottaghy K. Species differences in platelet aggregation with special reference to heparin as anticoagulant. Basis Aspects of Blood Trauma. 1979; pp.80-97. eds: H. Schmid-Schönbein, P. Teitel. Martinius Nijhoff Pub. The Hague Boston. London. doi: 10.1007/978-94-009-9337-2_5
1978 Mottaghy K, Zander M, Busch L. Bluttraumatisierung in Oxygenatoren unter standardisierten Bedingungen am Beispiel eines Bubble-Oxygenators. Biomedizinische Technik 23. 1978; 124-125. doi: 10.1515/bmte.1978.23.s1.248
1977 Mottaghy K, Driessen G, Zander M, Kreisel C, Mendler N, Schmid-Schönbein H. The floating-droplets oxygenator: Developments using fluorocarbons with coaxial rotating cylinders. Trans. Am. Soc. Artif. Intern. Organs. 1977; 23: 464-468
1977 Mottaghy K, Schumacher E, Schmid-Schönbein H. A new blood pumping method: The gravity pump. Proc. Eur. Soc. Artif. Organs IV. 1977; 593-599
1976 Mottaghy K, Mendler N, Schmid-Schönbein H, Schröck R, Sebening F. A new type of fluorocarbon liquid oxygenator. Eur. surg. Res. 1976; 8: 196-203. doi: 10.1159/000127865